Study Shows Effectiveness of Rigorous Prevention Measures in NICUs During Viral Surges

OHSU research shows masking, visitor screening, and strict hand hygiene practices reduce viral infections in vulnerable newborns, even outside of pandemic conditions.

Daniel Beaird

Feb. 17, 2026

Key Highlights

Implementation of universal masking and strict hygiene protocols led to a notable reduction in NICU infection rates.
Visitor restrictions and health screenings contributed to creating a safer environment for newborns in intensive care.
The study underscores the importance of infection prevention strategies during seasonal viral peaks to protect vulnerable infants.

A recent study from Oregon Health & Science University (OHSU) demonstrates that enhanced infection prevention strategies in neonatal intensive care units (NICUs) can dramatically lower the risk of viral infections in the most vulnerable infants. Published in JAMA Network Open, the research examined data from 12 NICUs across the U.S. and Canada.

The study found that practices such as universal masking, strict health screenings for visitors and staff, rigorous hand hygiene, and restricted visitation were associated with a significant reduction in healthcare-associated infections, even as viral illnesses surged in the broader community. During the study period, infection rates in NICU patients fell from roughly 0.8% to 0.3%, highlighting the effectiveness of these preventive measures.

Researchers suggest that these strategies could be beneficial beyond pandemic situations, particularly during seasonal spikes in respiratory viruses, offering critical protection for infants with developing immune systems.