Study Finds Brief Contact With Contaminated Surface Affects Sterility of Surgical Implants

Certain disinfection methods can reduce, but not eliminate, contamination, but replacement of the implant is the only way to fully safeguard against it.
March 27, 2026
2 min read

Key Highlights

  • Brief contact with contaminated surfaces can introduce microbes to surgical implants, potentially leading to infections.
  • Disinfection with chlorhexidine gluconate or povidone-iodine significantly reduces bacterial contamination but does not guarantee complete sterilization.
  • Ethanol and no intervention are less effective than CHG and PI in reducing microbial presence on contaminated implants.
  • In cases of contamination, replacing dropped implants is preferable to disinfection when possible.
  • Patients should be informed of contamination events and monitored for signs of infection to ensure prompt treatment.

A study published in Infection Control & Hospital Epidemiology found that “even brief contact with a contaminated surface can affect the sterility of surgical implants.” CIDRAP has the news.

In addition, the study found that “certain disinfection methods can reduce, but not fully eliminate, contamination.”

The researchers “deliberately exposed 213 polyethylene (PE) implant liners from hip or knee implants to contamination by placing them on the operating room (OR) floor where the surgeon had stood for 10 seconds immediately following orthopedic surgery.” They then divided each implant in half and “swabbed one half for bacteria before applying any antiseptic intervention and swabbed the other half after applying either chlorhexidine gluconate (CHG) and alcohol, povidone and iodine (PI), or ethanol (EtOH) as disinfectants. The control consisted of no disinfection.”

The CHG and PI immersions “reduced the pathogens on the implants better than EtOH or the control group. Median bacterial counts fell from 10 (0 to 60) colony-forming units (CFU) before disinfection to 0 (0 to 20) CFU after, with CHG and PI performing similarly and both significantly reducing bacterial counts better than the control.”

These results underscore that “even brief exposure to nonsterile environments can introduce microbes that are not easily or fully removed from implants, and that, whenever possible, dropped implants should be replaced rather than disinfected.” Immersion in sterile CHG or PI is “preferable to ethanol or no intervention” if an alternative is unavailable, but “patients should be informed of the event and monitored for signs of infection.”

About the Author

Matt MacKenzie

Associate Editor

Matt is Associate Editor for Healthcare Purchasing News.

Sign up for our eNewsletters
Get the latest news and updates