DHP systems reduced levels of environmental contamination detected on surfaces by up to 99.5%

April 21, 2021

Synexis LLC announced a study evaluating the use of dry hydrogen peroxide (DHP) technology in a clinical setting. 

The study, published online in the American Journal of Infection Control, assessed the efficacy of using DHP technology, in conjunction with standard manual cleaning, in reducing microbial contamination in the air and on surfaces at Sunrise Hospital and Medical Center and Sunrise Children’s Hospital, acute care facilities located in Las Vegas. 

“Numerous studies show that even after manual cleaning, as many as 50% of surfaces remain contaminated with pathogens, including multidrug-resistant organisms. As the primary investigator, I’m proud of our study results showing the effectiveness of DHP technology in reducing both air and surface microbial contamination,” said Jennifer Sanguinet, DrPh, FAPIC, CIC, MBA-HCM, BSIS, Principal Investigator. 

Microbial burden levels were measured from air and surface samples collected before and after technology activation during the 28-day study. Routine manual cleaning operations were continued throughout the study time frame. Surface samples included those collected from high-touch surfaces (privacy curtains, bed rails and nursing counters) and one low-touch surface (top of proximity cabinet). When compared to the average number of bacteria present on surfaces measured before activating DHP technology, the study reported a statistically significant 96.5% reduction in the average number of bacteria observed in all surface samples after one day of continuous operation of the appliance, and an overall reduction of 92.0% on sampled surfaces was being sustained by Day 28. Samples taken on hard surfaces reflected a decrease of 94.3% after one day of DHP technology treatment, maintaining an 88.8% reduction after 28 days of continuous operation of the appliance. The highest levels of reduction were seen on harder-to-clean, soft surfaces (privacy curtains; 99.5% on Day 1; 96.6% on Day 28). 

Study investigators analyzed the samples by Genus ID to identify which organisms were present. The predominant organisms before DHP treatment included bacteria such as those found in normal skin flora and Acinetobacter lwoffii, a pathogenic bacterium linked to infections that can survive for long periods on surfaces. DHP was effective in the reduction of predominant Gram-negative rod throughout the experiment, and Acinetobacter lwoffii was no longer identified as the primary microorganism present in samples taken from surfaces after one week of continuous operation of the DHP technology. 

Synexis has the article.